Breaking: US Launches Operation Against Iran — First Strikes Hit Nuclear and Military Sites

United States February 27, 2026 3 min read

Operation Begins: US Forces Strike Iran

At approximately 20:00 UTC on February 27, 2026, United States Central Command (CENTCOM) initiated a coordinated military operation against the Islamic Republic of Iran. The first wave of strikes targeted Iran's nuclear infrastructure and key military command-and-control nodes in what Pentagon officials described as a 'decisive action to prevent nuclear breakout.'

Opening Salvo: Cruise Missiles and Stealth Bombers

The operation's opening phase combined sea-launched Tomahawk cruise missiles from Arleigh Burke-class destroyers in the Persian Gulf with B-2 Spirit stealth bombers flying from Diego Garcia. The B-2s carried GBU-57 Massive Ordnance Penetrators — 30,000-pound bunker-busting bombs designed specifically to reach deeply buried facilities like Iran's Fordow enrichment plant.

Simultaneously, F-35I Adir fighters operating from undisclosed bases suppressed Iranian air defenses using AGM-88 HARM anti-radiation missiles, clearing corridors for follow-on strikes.

Nuclear Sites: Primary Target Set

Intelligence assessments indicated Iran had accumulated over 440 kg of highly enriched uranium — enough for multiple nuclear weapons — with breakout time estimated at under two weeks. The strike package prioritized:

Iranian Air Defenses Respond

Iran's integrated air defense network, anchored by Russian-supplied S-300PMU-2 batteries and domestically produced Bavar-373 systems, attempted to engage incoming cruise missiles. Initial reports suggest partial success against Tomahawk volleys but limited effectiveness against stealth platforms. The Suppression of Enemy Air Defenses (SEAD) campaign appears to have degraded Iran's radar network within the first hours.

Global Reaction

Oil futures spiked immediately, with Brent crude jumping 15% in after-hours trading. The UN Security Council convened an emergency session. Israel confirmed it was coordinating with US forces, while Russia and China called for 'immediate cessation of hostilities.'

This analysis will be updated as the situation develops. Monitor real-time strikes on our Live Strike Map and track missile defense performance on the Interceptors Tab.

Frequently Asked Questions

When did the US-Iran war start?

The US-Iran conflict began on February 27, 2026, when American forces launched precision strikes against Iranian nuclear facilities and military installations. The operation was initiated following months of escalating tensions. Track the full timeline on our <a href='#strikes'>Strike Dashboard</a>.

What weapons were used in the first US strikes on Iran?

The initial strikes employed Tomahawk cruise missiles launched from naval vessels in the Persian Gulf, B-2 Spirit stealth bombers carrying GBU-57 Massive Ordnance Penetrators for hardened nuclear sites, and F-35I Adir fighter jets. See detailed weapon profiles in our <a href='/weapons/tomahawk/'>Tomahawk</a> and <a href='/weapons/b-2-spirit/'>B-2 Spirit</a> analysis pages.

Which Iranian sites were targeted first?

Initial targets included the Natanz uranium enrichment facility, Fordow underground enrichment plant, Isfahan nuclear technology center, and several IRGC military command nodes. View facility damage assessments on our <a href='#nuclear'>Nuclear Tab</a>.

Related Intelligence Topics

Nuclear Breakout Timeline Tomahawk Cruise Missile B-2 Spirit Stealth Bomber US CENTCOM Profile Nuclear Status Tracker F-35I Adir Profile
US-Iran WarIranNuclearTomahawkB-2 SpiritFirst StrikeCENTCOM